Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7657350 | 0.99 | CA1 (0.52) | CA1CA2CA9ENPP2MKNK1 | |
| Hydrochloric Acid SCHEMBL7650974 | 0.95 | ADH5 (0.51) | CA1CA2CA9ENPP2MKNK1 | |
| Hydrochloric Acid SCHEMBL7658202 | 0.95 | ADH5 (0.51) | CA1CA2CA9ENPP2MKNK1 | |
| SCHEMBL10423949 | 0.91 | ENPP2 (0.59) | CA1CA2CA9ENPP2MKNK1 | |
| SCHEMBL7657342 | 0.87 | CA1 (0.52) | CA1CA2CA9ENPP2MKNK1 | |
| Hydrochloric Acid SCHEMBL7653313 | 0.85 | KDM4E (0.57) | CA1CA2CA9KDM4EUSP2 | |
| SCHEMBL10512975 | 0.84 | LMNA (0.62) | ENPP2MKNK1MKNK2ALOX15TSHR | |
| SCHEMBL7650969 | 0.83 | ALOX15 (0.53) | CA1CA2CA9ENPP2MKNK1 | |
| SCHEMBL7658197 | 0.83 | ALOX15 (0.53) | CA1CA2CA9ENPP2MKNK1 | |
| Hydrochloric Acid SCHEMBL7661980 | 0.81 | NAMPT (0.42) | CA1CA2CA9KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339092-B1 | FOR THERAPY RHEUMATOID ARTHRITIS, ARTHROSIS, TUMOUR INVASION AND GROWTH, INCLUDING MALIGNANT SPREAD AND THE FORMATION OF METASTASES, ULCERATIONS, ATHEROSCLEROSIS | ADIR ET COMPAGNIE (FR) | 2002-01-15 | — | — | US | disclosed |