Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655128 | 0.88 | RAB9A (0.52) | MAPTRAB9ANPC1FAAHLMNA | |
| SCHEMBL7658421 | 0.85 | NPC1 (0.41) | MAPTRAB9ANPC1FAAHLMNA | |
| SCHEMBL7662218 | 0.79 | PTGS2 (0.42) | MAPTRAB9ANPC1LMNAKMT2A | |
| SCHEMBL7655633 | 0.75 | GRM2 (0.43) | KMT2AALDH1A1GAAPOLBMEN1 | |
| SCHEMBL7662979 | 0.75 | NPC1 (0.60) | MAPTRAB9ANPC1FAAHLMNA | |
| SCHEMBL7655647 | 0.74 | MAPT (0.51) | MAPTRAB9ALMNAKMT2AALDH1A1 | |
| SCHEMBL7659603 | 0.73 | SIRT2 (0.45) | MAPTRAB9ANPC1LMNAKMT2A | |
| SCHEMBL7659132 | 0.70 | KMT2A (0.62) | MAPTRAB9ANPC1LMNAKMT2A | |
| SCHEMBL7655836 | 0.70 | ALDH1A1 (0.50) | MAPTRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL7662426 | 0.69 | ADORA3 (0.43) | MAPTRAB9ANPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |