Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.42 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624736 | 0.79 | ALDH1A1 (0.49) | GAAHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16624684 | 0.78 | PDE4B (0.49) | GAAHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7656886 | 0.73 | PLA2G2A (0.54) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL8208888 | 0.72 | KDM4E (0.49) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL10926173 | 0.72 | PTGS2 (0.47) | KDM4EALDH1A1HSD17B10NPSR1MEN1 | |
| SCHEMBL7653509 | 0.70 | DPP4 (0.48) | HPGDKDM4EALDH1A1HSD17B10NPC1 | |
| SCHEMBL16624680 | 0.70 | ALDH1A1 (0.53) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL16505799 | 0.69 | HPGD (0.53) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL7663206 | 0.69 | PLA2G2A (0.58) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL28344367 | 0.69 | SHMT2 (0.56) | GAAHPGDKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |