Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 13/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658321 | 1.00 | ALOX15 (0.41) | ALOX15ULK1MAPT | |
| SCHEMBL7550281 | 0.87 | ULK1 (0.35) | ALOX15ULK1 | |
| SCHEMBL7550279 | 0.87 | ULK1 (0.35) | ALOX15ULK1 | |
| SCHEMBL7547455 | 0.82 | ULK1 (0.41) | ALOX15ULK1 | |
| SCHEMBL7653241 | 0.79 | ALOX15 (0.36) | ALOX15MAPT | |
| SCHEMBL7653239 | 0.79 | ALOX15 (0.36) | ALOX15MAPT | |
| SCHEMBL7550428 | 0.76 | ULK1 (0.41) | ALOX15ULK1 | |
| SCHEMBL9433015 | 0.70 | GRIN1 (0.66) | ALOX15ULK1 | |
| SCHEMBL30695188 | 0.69 | ALOX15 (0.62) | ALOX15MAPT | |
| SCHEMBL1093057 | 0.69 | ALOX15 (0.62) | ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495587-B1 | TREATING A DAMAGE TO THE CENTRAL NERVOUS SYSTEM INDUCED BY AN ISCHEMIC OR HYPOXIC CONDITION AND STROKE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1163220-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056711-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-09-28 | — | — | WO | disclosed |