Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653241 | 1.00 | ALOX15 (0.36) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7658317 | 0.79 | ALOX15 (0.41) | ALOX15MAPT | |
| SCHEMBL7658321 | 0.79 | ALOX15 (0.41) | ALOX15MAPT | |
| SCHEMBL7547774 | 0.76 | FBP1 (0.32) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7547773 | 0.76 | FBP1 (0.32) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7657461 | 0.67 | ALOX15 (0.38) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7550281 | 0.66 | ULK1 (0.35) | ALOX15 | |
| SCHEMBL7550279 | 0.66 | ULK1 (0.35) | ALOX15 | |
| SCHEMBL8122601 | 0.66 | ALDH1A1 (0.48) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8123821 | 0.63 | KDM4E (0.51) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495587-B1 | TREATING A DAMAGE TO THE CENTRAL NERVOUS SYSTEM INDUCED BY AN ISCHEMIC OR HYPOXIC CONDITION AND STROKE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1163220-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000056711-A1 | TRICYCLIC INDOLE-2-CARBOXYLIC ACID COMPOUND USED AS NMDA RECEPTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2000-09-28 | — | — | WO | disclosed |