Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | PTPRB | P23467 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660423 | 0.84 | SLC6A2 (0.42) | CAPN1TACR1 | |
| SCHEMBL7658402 | 0.83 | PTPRB (0.40) | YAP1PTPRBPTPN11STSTACR1 | |
| SCHEMBL7661897 | 0.83 | CTSB (0.50) | CTSBCTSSCTSKTACR1 | |
| SCHEMBL8720236 | 0.82 | PTPRB (0.42) | YAP1PTPRBPTPN11STSTACR1 | |
| SCHEMBL6162914 | 0.77 | MAPK1 (0.62) | YAP1CTSBCTSSCTSKCAPN1 | |
| SCHEMBL6162909 | 0.77 | MAPK1 (0.62) | YAP1CTSBCTSSCTSKCAPN1 | |
| SCHEMBL6600960 | 0.75 | USP30 (0.41) | YAP1PTPRBPTPN11STSTACR1 | |
| SCHEMBL7658151 | 0.74 | CTSS (0.67) | CTSBCTSSCTSKTACR1 | |
| SCHEMBL6168383 | 0.71 | MAPK1 (0.51) | YAP1CTSBCAPN1STSTACR1 | |
| SCHEMBL6168374 | 0.71 | MAPK1 (0.51) | YAP1CTSBCAPN1STSTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |