Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661900 | 0.83 | GHSR (0.39) | TACR1 | |
| SCHEMBL7658396 | 0.83 | YAP1 (0.43) | PTPRBTACR1PTPN11USP30STS | |
| SCHEMBL8720236 | 0.79 | PTPRB (0.42) | PTPRBTACR1PTPN11USP30STS | |
| SCHEMBL6600960 | 0.76 | USP30 (0.41) | PTPRBTACR1PTPN11USP30STS | |
| SCHEMBL2340961 | 0.72 | PTPRB (0.52) | PTPRBPTPN11USP30STSMEN1 | |
| SCHEMBL6162909 | 0.69 | MAPK1 (0.62) | STSYAP1MEN1KMT2A | |
| SCHEMBL6162914 | 0.69 | MAPK1 (0.62) | STSYAP1MEN1KMT2A | |
| SCHEMBL6600523 | 0.68 | ALDH1A1 (0.43) | PTPRBPTPN11USP30STSMEN1 | |
| SCHEMBL6319971 | 0.68 | YAP1 (0.42) | TACR1USP30STSYAP1GPR119 | |
| SCHEMBL3640283 | 0.67 | KDM4E (0.54) | STSYAP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |