Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | PTPRB | P23467 | 9/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519418 | 1.00 | CTSB (0.52) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL27478624 | 0.93 | CTSS (0.53) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL6600491 | 0.93 | CTSS (0.53) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL27552033 | 0.91 | CTSS (0.52) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL6600308 | 0.91 | CTSS (0.52) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL6599351 | 0.85 | CTSS (0.56) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL8240165 | 0.76 | CTSS (0.55) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL6604430 | 0.75 | CTSS (0.44) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL6600260 | 0.74 | CTSC (0.45) | CTSBCTSSCTSKPTPRBPTPN1 | |
| SCHEMBL27494688 | 0.74 | CTSC (0.45) | CTSBCTSSCTSKPTPRBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225471-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2005-11-02 | — | — | CN | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| CN-1176645-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1998-03-18 | — | — | CN | disclosed |