SCHEMBL765857

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755124	0.92	DRD2 (0.40)	LIPGRXFP1PPARGNCOR2PARP1
	SCHEMBL754447	0.86	LIPG (0.41)	LIPGLMNAALDH1A1POLB
	SCHEMBL754217	0.85	LIPG (0.40)	LIPGRXFP1LMNAALDH1A1POLB
	SCHEMBL752965	0.85	LIPG (0.41)	LIPGLMNAALDH1A1POLB
	SCHEMBL2489852	0.84	LIPG (0.44)	LIPGHTTRAB9AALDH1A1POLB
	SCHEMBL2486832	0.83	ALDH1A1 (0.41)	LIPGLMNAALDH1A1POLB
	SCHEMBL752862	0.83	LIPG (0.41)	LIPGHTTLMNAPARP1ALDH1A1
	SCHEMBL752899	0.81	LIPG (0.51)	LIPGLMNAALDH1A1POLB
	SCHEMBL753279	0.81	ALDH1A1 (0.46)	LIPGHTTLMNAALDH1A1POLB
	SCHEMBL754682	0.81	ALDH1A1 (0.39)	LIPGRXFP1KMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.