Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979382 | 0.82 | LSS (0.48) | POLBLSSALDH1A1GBA1KDM4E | |
| SCHEMBL6978270 | 0.76 | LSS (0.48) | POLBLSSALDH1A1GBA1KDM4E | |
| SCHEMBL8522043 | 0.75 | LSS (0.48) | POLBLSSALDH1A1GBA1KDM4E | |
| SCHEMBL6973403 | 0.69 | SORD (0.45) | LSSALDH1A1GBA1KDM4EHSD17B10 | |
| SCHEMBL7658217 | 0.67 | LSS (0.66) | LSSALDH1A1GBA1KDM4EMEN1 | |
| SCHEMBL15916747 | 0.66 | KDM4E (0.69) | POLBALDH1A1GBA1KDM4ECHRM4 | |
| SCHEMBL15915961 | 0.66 | SMN1; SMN2 (0.64) | POLBALDH1A1GBA1KDM4EMEN1 | |
| SCHEMBL9514844 | 0.66 | ALDH1A1 (0.52) | LSSALDH1A1GBA1MEN1KMT2A | |
| SCHEMBL9513912 | 0.66 | LMNA (0.53) | LSSALDH1A1GBA1KDM4ECTSS | |
| SCHEMBL8466387 | 0.66 | LSS (0.48) | LSSALDH1A1GBA1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |