Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.50 |
| ▸ | MMP9 | P14780 | 13/20 | 0.50 |
| ▸ | MMP13 | P45452 | 13/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951866 | 0.93 | MMP13 (0.51) | MMP1MMP9MMP13ALDH1A1 | |
| Diethylamine SCHEMBL7074643 | 0.85 | MMP1 (0.57) | MMP1MMP9MMP13SMN1; SMN2ALDH1A1 | |
| Ethylamine SCHEMBL7643008 | 0.84 | MMP1 (0.57) | MMP1MMP9MMP13SMN1; SMN2ALDH1A1 | |
| Diethylamine SCHEMBL7071575 | 0.81 | MMP13 (0.55) | MMP1MMP9MMP13SMN1; SMN2ALDH1A1 | |
| SCHEMBL7072869 | 0.80 | MMP13 (0.56) | MMP1MMP9MMP13ALDH1A1 | |
| SCHEMBL7074641 | 0.76 | MMP1 (0.78) | MMP1MMP9MMP13SMN1; SMN2 | |
| Diethylamine SCHEMBL7073267 | 0.75 | MMP1 (0.58) | MMP1MMP9MMP13SMN1; SMN2ALDH1A1 | |
| Diethylamine SCHEMBL6933694 | 0.73 | MMP13 (0.74) | MMP1MMP9MMP13 | |
| Diethylamine SCHEMBL7066430 | 0.73 | MMP1 (0.56) | MMP1MMP9MMP13SMN1; SMN2ALDH1A1 | |
| Diethylamine SCHEMBL7073053 | 0.72 | MMP13 (0.57) | MMP1MMP9MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441023-B1 | FOR THERAPY OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, DIABETES (INSULIN RESISTANCE) AND HIV INFECTION | AMERICAN HOME PRODUCTS CORPORATION | 2002-08-27 | — | — | US | disclosed |
| US-20020032186-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | AMERICAN CYANAMID COMPANY (US) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032186-A1 | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors | MMP12, ADAM33, MMP2 | MMP1 4/4885MMP9 13/4885MMP13 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.