Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 6/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843230 | 0.74 | RIPK1 (0.49) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL9843140 | 0.72 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL27717225 | 0.72 | RIPK1 (0.49) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL5890987 | 0.70 | LMNA (0.69) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL8057291 | 0.70 | RIPK1 (0.64) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL9718704 | 0.70 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL9800159 | 0.70 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7671954 | 0.70 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL9800154 | 0.70 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7665299 | 0.70 | LMNA (0.48) | RIPK1CHRNB2CHRNA4LMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |