Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.40 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800159 | 1.00 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL27717225 | 0.82 | RIPK1 (0.49) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7671954 | 0.80 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7669212 | 0.80 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL9718704 | 0.80 | RIPK1 (0.47) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL8560242 | 0.79 | RIPK1 (0.46) | RIPK1CHRNB2CHRNA4LMNANAMPT | |
| SCHEMBL7670556 | 0.79 | MMP2 (0.34) | LMNAALDH1A1HTT | |
| SCHEMBL7660230 | 0.79 | AGTR2 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9045171 | 0.79 | AGTR2 (0.39) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7686987 | 0.78 | RIPK1 (0.48) | RIPK1CHRNB2CHRNA4LMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049571-A | Insecticides | CIBA-GEIGY CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-4918086-A | PESTICIDES, INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |