Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688074 | 0.87 | PRKCI (0.53) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL2771783 | 0.86 | MMP12 (0.59) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL15245751 | 0.84 | LOXL2 (0.59) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL27787243 | 0.82 | CLK4 (0.63) | XDHSLC22A12PTPN5CLK4PGR | |
| SCHEMBL10244532 | 0.82 | CYP2A6 (0.57) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL9846008 | 0.82 | MMP12 (0.51) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL8982347 | 0.82 | CYP2A6 (0.57) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL16675765 | 0.82 | PRKCI (0.56) | MMP12MMP13HDAC8MMP3PRKCI | |
| SCHEMBL19608719 | 0.81 | TSHR (0.58) | MMP12MMP13HDAC8XDHSLC22A12 | |
| SCHEMBL12807987 | 0.81 | MMP3 (0.58) | MMP12MMP13HDAC8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |