Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667644 | 0.96 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR1AMEN1KMT2A | |
| SCHEMBL7664078 | 0.93 | SIGMAR1 (0.62) | SIGMAR1DRD2HTR1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7667688 | 0.92 | SIGMAR1 (0.61) | SIGMAR1DRD2HTR1AMEN1KMT2A | |
| Phosphoric Acid SCHEMBL7658559 | 0.92 | SIGMAR1 (0.55) | SIGMAR1DRD2HTR1AMEN1KMT2A | |
| Fumaric Acid SCHEMBL7658099 | 0.89 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR1APARP1PPARG | |
| Fumaric Acid SCHEMBL7658104 | 0.89 | SIGMAR1 (0.53) | SIGMAR1DRD2HTR1APARP1PPARG | |
| Citric Acid SCHEMBL7665179 | 0.85 | SIGMAR1 (0.48) | SIGMAR1DRD2HTR1APARP1PPARG | |
| SCHEMBL5846061 | 0.82 | SIGMAR1 (0.60) | SIGMAR1DRD2HTR1AMEN1KMT2A | |
| SCHEMBL918431 | 0.78 | SIGMAR1 (0.60) | SIGMAR1DRD2HTR1APARP1 | |
| SCHEMBL5846267 | 0.76 | SIGMAR1 (0.60) | SIGMAR1DRD2HTR1APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355659-B1 | TREATING PSYCHOSIS AND DEMENTIA BY ADMINISTERING | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-03-12 | — | — | US | claimed |
| US-6355659-B1 | TREATING PSYCHOSIS AND DEMENTIA BY ADMINISTERING | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2002-03-12 | — | — | US | disclosed |