Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 4/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666709 | 0.85 | ALOX5 (0.38) | ALDH1A1LMNAKMT2AMAPTALOX5 | |
| SCHEMBL7701579 | 0.81 | ALOX5 (0.43) | ALDH1A1HTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL6346594 | 0.78 | ALDH1A1 (0.46) | GSK3BCASP3CASP2ALDH1A1HTT | |
| SCHEMBL11256931 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HTTLMNASMN1; SMN2KMT2A | |
| SCHEMBL8760971 | 0.75 | ALDH1A1 (0.65) | GSK3BCASP3CASP2ALDH1A1HTT | |
| SCHEMBL30100972 | 0.72 | NPC1 (0.46) | GSK3BCASP3CASP2LMNAKMT2A | |
| SCHEMBL10491647 | 0.72 | PREP (0.40) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL10593276 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HTTLMNAKMT2AMEN1 | |
| SCHEMBL14378273 | 0.71 | ALOX5 (0.35) | ALDH1A1HTTLMNAKMT2AMAPT | |
| SCHEMBL10703343 | 0.71 | CTSV (0.45) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-219849581-U | Synthesis equipment for preparing 2-chloro-N- (cyano-2-thiophenemethyl) acetamide | 营口昌成新材料科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-219849581-U | Synthesis equipment for preparing 2-chloro-N- (cyano-2-thiophenemethyl) acetamide | 营口昌成新材料科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-219849581-U | Synthesis equipment for preparing 2-chloro-N- (cyano-2-thiophenemethyl) acetamide | 营口昌成新材料科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-219849581-U | Synthesis equipment for preparing 2-chloro-N- (cyano-2-thiophenemethyl) acetamide | 营口昌成新材料科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-1137121-C | Process for the preparation of 2-aminothiazolecarboxamide derivatives | LG��ѧ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| US-6388096-B2 | MICROBIOCIDES AGAINST PLANT DISEASE | LG CHEMICAL LTD. (KR) | 2002-05-14 | — | — | US | disclosed |
| US-20020010340-A1 | Process for preparation of 2-aminothiazolecarboxamide derivatives | LG CHEMICAL LTD. | 2002-01-24 | — | — | US | disclosed |
| US-6277995-B1 | REACTING PHENYLIMINOALKYL-THIOUREA COMPOUND WITH 2-BROMO(OR CHLORO)-N-(.ALPHA.-CYANO-2-THENYL)ACETAMIDE IN PRESENCE OF SOLVENT AND BASE TO FORM 2-AMINOTHIAZOLECARBOXAMIDE COMPOUND | LG CHEMICAL LTD. (KR) | 2001-08-21 | — | — | US | disclosed |
| CN-1277610-A | Process for the preparation of 2-aminothiazolecarboxamide derivatives | LG CHEMICAL LTD (KR) | 2000-12-20 | — | — | CN | disclosed |
| EP-1045848-A1 | PROCESS FOR PREPARATION OF 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVES | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | disclosed |
| WO-2000018766-A1 | PROCESS FOR PREPARATION OF 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVES | LG CHEMICAL LTD. (KR) | 2000-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010340-A1 | Process for preparation of 2-aminothiazolecarboxamide derivatives | CBR1, CBR3, CYP1B1 | GSK3B 3805/4885CASP3 2487/4885CASP2 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.