Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 5/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664906 | 0.85 | GSK3B (0.44) | ALOX5CTSCCES2CES1KEAP1 | |
| SCHEMBL7701579 | 0.81 | ALOX5 (0.43) | ALOX5CTSCCES2CES1KEAP1 | |
| SCHEMBL10593276 | 0.72 | ALDH1A1 (0.54) | KMT2ATSHRALDH1A1LMNATHRB | |
| SCHEMBL14378273 | 0.71 | ALOX5 (0.35) | ALOX5CTSCCES2CES1KEAP1 | |
| SCHEMBL7412736 | 0.71 | MEN1 (0.40) | CTSCKMT2AALDH1A1POLBKDM4E | |
| SCHEMBL6063016 | 0.71 | CTSC (0.43) | CTSCTSHRALDH1A1LMNATP53 | |
| SCHEMBL10703343 | 0.71 | CTSV (0.45) | KMT2AALDH1A1MAPTTP53CTSL | |
| SCHEMBL10654251 | 0.71 | CTSL (0.45) | ALDH1A1POLBMAPTCTSL | |
| SCHEMBL9555506 | 0.70 | PRKCI (0.46) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL8799895 | 0.70 | RAB9A (0.46) | KMT2AALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137121-C | Process for the preparation of 2-aminothiazolecarboxamide derivatives | LG��ѧ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| US-6388096-B2 | MICROBIOCIDES AGAINST PLANT DISEASE | LG CHEMICAL LTD. (KR) | 2002-05-14 | — | — | US | disclosed |
| US-6277995-B1 | REACTING PHENYLIMINOALKYL-THIOUREA COMPOUND WITH 2-BROMO(OR CHLORO)-N-(.ALPHA.-CYANO-2-THENYL)ACETAMIDE IN PRESENCE OF SOLVENT AND BASE TO FORM 2-AMINOTHIAZOLECARBOXAMIDE COMPOUND | LG CHEMICAL LTD. (KR) | 2001-08-21 | — | — | US | disclosed |
| CN-1277610-A | Process for the preparation of 2-aminothiazolecarboxamide derivatives | LG CHEMICAL LTD (KR) | 2000-12-20 | — | — | CN | disclosed |
| EP-1045848-A1 | PROCESS FOR PREPARATION OF 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVES | LG CHEMICAL LIMITED (KR) | 2000-10-25 | — | — | EP | disclosed |
| WO-2000018766-A1 | PROCESS FOR PREPARATION OF 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVES | LG CHEMICAL LTD. (KR) | 2000-04-06 | — | — | WO | disclosed |