Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664906 | 0.81 | GSK3B (0.44) | ALOX5ALDH1A1CTSCCES2CES1 | |
| SCHEMBL7666709 | 0.81 | ALOX5 (0.38) | ALOX5ALDH1A1CTSCCES2CES1 | |
| SCHEMBL7723792 | 0.76 | ALDH1A1 (0.52) | ALOX5ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8799895 | 0.75 | RAB9A (0.46) | ALDH1A1NPC1L3MBTL1RAB9AMEN1 | |
| SCHEMBL10585741 | 0.74 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CYP2C19GFERL3MBTL1 | |
| SCHEMBL10593276 | 0.74 | ALDH1A1 (0.54) | ALDH1A1CYP2C19RAB9ATSHRMEN1 | |
| SCHEMBL14378273 | 0.73 | ALOX5 (0.35) | ALOX5ALDH1A1CTSCCES2CES1 | |
| SCHEMBL10703343 | 0.73 | CTSV (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19NPC1 | |
| SCHEMBL10654251 | 0.73 | CTSL (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19GAA | |
| SCHEMBL11448104 | 0.73 | ALOX5 (0.47) | ALOX5ALDH1A1CYP2C9CYP2C19CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010340-A1 | Process for preparation of 2-aminothiazolecarboxamide derivatives | LG CHEMICAL LTD. | 2002-01-24 | — | — | US | disclosed |
| EP-1045848-B1 | PROCESS FOR PREPARATION OF 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVES | LG CHEMICAL LTD (KR) | 2001-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010340-A1 | Process for preparation of 2-aminothiazolecarboxamide derivatives | CBR1, CBR3, CYP1B1 | ALOX5 126/4885ALDH1A1 220/4885CYP3A4 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.