Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.60 |
| ▸ | MMP1 | P03956 | 4/20 | 0.60 |
| ▸ | MMP3 | P08254 | 4/20 | 0.60 |
| ▸ | MMP9 | P14780 | 4/20 | 0.60 |
| ▸ | MMP8 | P22894 | 4/20 | 0.60 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480352 | 0.84 | MMP2 (0.81) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL7480347 | 0.84 | MMP2 (0.81) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL7483182 | 0.76 | MMP1 (0.79) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL4312415 | 0.75 | MMP1 (1.00) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL7479388 | 0.74 | MMP1 (0.75) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL5701852 | 0.74 | POLB (0.49) | ALDH1A1PKMSMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL5702166 | 0.74 | POLB (0.49) | ALDH1A1PKMSMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL7428159 | 0.72 | MMP1 (0.80) | MMP2MMP1MMP3MMP9MMP8 | |
| SCHEMBL2535135 | 0.67 | EHMT2 (0.47) | ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL2535132 | 0.67 | EHMT2 (0.47) | ALDH1A1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399598-B1 | ORAL DISEASES; RHEUMATIC DISEASES; OSTEOPOROSIS | THE PROCTER & GAMBLE COMPANY | 2002-06-04 | — | — | US | disclosed |