Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662242 | 0.87 | PDK2 (0.41) | MAOAMAOBS1PR1TDP2PDK2 | |
| SCHEMBL7661597 | 0.84 | PLK1 (0.39) | MAOAMAOBS1PR1TDP2CETP | |
| SCHEMBL7659369 | 0.83 | PLK1 (0.44) | MAOAMAOBS1PR1HTR2AHTR2C | |
| SCHEMBL7662259 | 0.82 | PLK1 (0.46) | S1PR1HTR2AHTR2CALDH1A1LMNA | |
| SCHEMBL7660282 | 0.79 | GRIN2B (0.45) | MAOAMAOBALDH1A1 | |
| SCHEMBL7662248 | 0.79 | SRD5A1 (0.42) | MAOAMAOBKCNH2NPC1ALDH1A1 | |
| SCHEMBL7659930 | 0.77 | KIF11 (0.47) | TDP2NOTUMPARP1PARP10HTR2A | |
| SCHEMBL21758076 | 0.77 | RAB9A (0.52) | PDK2NPC1ALDH1A1LMNAMAPT | |
| SCHEMBL7664919 | 0.76 | MAOB (0.50) | MAOAMAOBPDK2ALDH1A1LMNA | |
| SCHEMBL5683744 | 0.75 | TDP2 (0.45) | MAOAMAOBS1PR1TDP2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |