Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19422232 | 0.83 | PARP10 (0.55) | PARP10PARP11SRD5A1NOTUMPARP1 | |
| SCHEMBL33527314 | 0.77 | TDP2 (0.59) | KIF11TDP2PARP10PARP1HTR2A | |
| SCHEMBL7666138 | 0.77 | MAOA (0.41) | TDP2PARP10NOTUMPARP1HTR2A | |
| SCHEMBL7664100 | 0.77 | CYP24A1 (0.59) | CYP26A1CYP24A1 | |
| SCHEMBL7665011 | 0.76 | PARP10 (0.46) | KIF11PARP10PARP11SRD5A1METAP1 | |
| SCHEMBL7668079 | 0.75 | GPR3 (0.58) | PARP10PARP11SRD5A1GPR3METAP1 | |
| SCHEMBL2388879 | 0.74 | CASP1 (0.55) | TDP2PARP10PARP11NOTUMPARP1 | |
| SCHEMBL26375481 | 0.74 | KIF11 (0.49) | KIF11NFE2L2GPR3 | |
| SCHEMBL7662242 | 0.74 | PDK2 (0.41) | TDP2PARP10NOTUMPARP1HTR2A | |
| SCHEMBL6853221 | 0.74 | SRD5A1 (0.52) | PARP10PARP11SRD5A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |