Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671944 | 0.95 | NR3C1 (0.37) | SMN1; SMN2DRD2DRD4DRD3MAPT | |
| SCHEMBL7667975 | 0.93 | ALDH1A1 (0.43) | SMN1; SMN2PTGER1MAPTTP53ALDH1A1 | |
| SCHEMBL7838035 | 0.93 | DRD2 (0.38) | SMN1; SMN2DRD2DRD4DRD3MAPT | |
| SCHEMBL7671654 | 0.93 | DRD2 (0.38) | SMN1; SMN2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL7667997 | 0.93 | SMN1; SMN2 (0.39) | SMN1; SMN2DRD2DRD4DRD3MAPT | |
| SCHEMBL7660651 | 0.91 | DRD2 (0.39) | DRD2DRD4DRD3MAPTF2 | |
| SCHEMBL7663075 | 0.91 | DRD4 (0.39) | SMN1; SMN2DRD2DRD4DRD3MAPT | |
| SCHEMBL7663132 | 0.91 | NR3C1 (0.34) | SMN1; SMN2DRD2DRD4DRD3MAPT | |
| SCHEMBL7671411 | 0.91 | DRD2 (0.39) | DRD2DRD4DRD3MAPTF2 | |
| Cadaverine Tartrate SCHEMBL7673468 | 0.89 | KEAP1 (0.38) | SMN1; SMN2MAPTTP53NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |