Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671944 | 0.97 | NR3C1 (0.37) | SMN1; SMN2NPC1RAB9AMAPTPGR | |
| SCHEMBL7838035 | 0.96 | DRD2 (0.38) | SMN1; SMN2NPC1RAB9AMAPTPGR | |
| SCHEMBL7671654 | 0.94 | DRD2 (0.38) | SMN1; SMN2PGRNR3C1DRD2DRD4 | |
| SCHEMBL7663132 | 0.93 | NR3C1 (0.34) | SMN1; SMN2NPC1RAB9AMAPTPGR | |
| SCHEMBL7660651 | 0.93 | DRD2 (0.39) | RAB9AMAPTPGRNR3C1DRD2 | |
| SCHEMBL7667872 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1MAPTDRD2DRD4 | |
| SCHEMBL7671411 | 0.93 | DRD2 (0.39) | RAB9AMAPTPGRNR3C1DRD2 | |
| SCHEMBL7667975 | 0.93 | ALDH1A1 (0.43) | SMN1; SMN2MAPTKEAP1NFE2L2MEN1 | |
| SCHEMBL7663075 | 0.93 | DRD4 (0.39) | SMN1; SMN2NPC1RAB9AMAPTPGR | |
| Cadaverine Tartrate SCHEMBL7673468 | 0.92 | KEAP1 (0.38) | SMN1; SMN2NPC1RAB9AMAPTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1072587-A1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-01-31 | — | — | EP | disclosed |