Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663439 | 0.97 | DPP4 (0.47) | DPP4RENACEPREPTACR1 | |
| SCHEMBL7665715 | 0.94 | DPP4 (0.47) | DPP4RENACEPREPCTSL | |
| SCHEMBL7670814 | 0.92 | REN (0.49) | DPP4RENPREPCTSLCTSB | |
| SCHEMBL7668437 | 0.91 | DPP4 (0.55) | DPP4RENACEPREPCTSL | |
| SCHEMBL7668101 | 0.90 | PREP (0.48) | DPP4RENACEPREPALDH1A1 | |
| SCHEMBL7665547 | 0.90 | DPP4 (0.45) | DPP4RENACEPREPCTSL | |
| SCHEMBL7669206 | 0.90 | DPP4 (0.42) | DPP4RENPREPCTSLALDH1A1 | |
| SCHEMBL7664388 | 0.89 | ADORA3 (0.45) | DPP4RENPREP | |
| SCHEMBL7668192 | 0.89 | CAPN1 (0.49) | DPP4RENPREPCTSLCYP3A4 | |
| SCHEMBL7669769 | 0.88 | CASP1 (0.43) | DPP4RENPREPALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |