SCHEMBL7670952

SCHEMBL7670952

CC(Cc1cc2c(cn1)[nH]c1ccccc12)(C(=O)NC(CO)Cc1ccccc1)N(C(=O)O)C1C2CC3CC(C2)CC1C3

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
CCKBR P32239 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7664675 0.84 NPY5R (0.32) CCKBR
SCHEMBL6897076 0.81 CCKBR (0.51) CCKBR
SCHEMBL6897079 0.81 CCKBR (0.51) CCKBR
SCHEMBL7665154 0.80 CCKBR (0.35) CCKBR
SCHEMBL7666814 0.78 NPY1R (0.37) CCKBR
SCHEMBL7664606 0.78 CYP3A4 (0.38)
SCHEMBL9700903 0.78 ALDH1A1 (0.45) ALDH1A1CCKBRMEN1KMT2A
SCHEMBL9538871 0.78 GABRA1 (0.41) ALDH1A1CCKBRMEN1KMT2A
SCHEMBL7667464 0.75 CYP3A4 (0.34) CCKBR
SCHEMBL7669675 0.71 CCKBR (0.37) CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6492531-B1 THE INVENTION CONCERNS CHOLECYSTOKININ (CCK) ANTAGONISTS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS. ESPECIALLY USEFUL ARE CCK.SUB.B ANTAGONISTS SUCH AS CI-988. WARNER-LAMBERT COMPANY 2002-12-10 US disclosed