Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 19/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678096 | 0.85 | MAPT (0.54) | — | |
| SCHEMBL7956599 | 0.83 | PYCR1 (0.43) | EIF4E | |
| SCHEMBL7535129 | 0.82 | EIF4E (0.47) | EIF4E | |
| SCHEMBL7788713 | 0.82 | THRB (0.44) | EIF4E | |
| SCHEMBL7669493 | 0.77 | RAB9A (0.53) | — | |
| SCHEMBL7118149 | 0.77 | KDM4E (0.53) | — | |
| SCHEMBL7676395 | 0.77 | MAPT (0.54) | EIF4E | |
| SCHEMBL1208143 | 0.76 | EIF4E (0.70) | EIF4E | |
| SCHEMBL7675100 | 0.76 | MAPT (0.56) | — | |
| SCHEMBL8018616 | 0.72 | ATP4A (0.42) | EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380187-B2 | FUNGICIDES | YU DINGWEI TIM (US) | 2002-04-30 | — | — | US | disclosed |
| US-6281217-B2 | ANTIFUNGAL ACTIVITY AGAINST A VARIETY OF FUNGI INCLUDING STRAINS WHICH HAVE PROVEN TO BE RESISTANT TO TREATMENT WITH KNOWN ANTIFUNGAL AGENTS SUCH AS FLUCONAZOLE. | YU DINGWEI TIM (US) | 2001-08-28 | — | — | US | disclosed |
| US-6277873-B1 | CONTROLLING DRUG RESISTANT FUNGI | YU DINGWEI TIM (US) | 2001-08-21 | — | — | US | disclosed |