SCHEMBL767177

SCHEMBL767177

CC(=O)C(=O)c1ccc(Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 5/20 0.71
CES1 P23141 5/20 0.71
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
NPC1 O15118 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NLRP1 Q9C000 1/20 0.48
GSK3B P49841 2/20 0.48
SRD5A2 P31213 1/20 0.48
MAPK1 P28482 1/20 0.48
HPGD P15428 2/20 0.47
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL273857 0.84 CES2 (1.00) CES2CES1ALOX15TSHRCA1
SCHEMBL4078516 0.81 CES2 (0.65) CES2CES1ALOX15TSHRCA1
SCHEMBL13444902 0.79 CES2 (0.64) CES2CES1MAPTNPC1RAB9A
SCHEMBL17187946 0.79 MAPT (0.69) CES2CES1ALOX15TSHRCA1
SCHEMBL75640 0.79 MAPT (0.69) CES2CES1ALOX15TSHRCA1
SCHEMBL29025701 0.79 CES2 (0.79) CES2CES1ALOX15TSHRCA1
SCHEMBL7679449 0.79 CES2 (0.56) CES2CES1ALOX15TSHRCA1
SCHEMBL7679447 0.79 CES2 (0.56) CES2CES1ALOX15TSHRCA1
Butane SCHEMBL9788851 0.78 CES2 (0.76) CES2CES1ALOX15TSHRCA1
SCHEMBL2156105 0.78 CES2 (1.00) CES2CES1ALOX15TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN claimed
EP-1432428-B1 Agent for colouring fibres containing keratin HENKEL KGAA (DE) 2006-11-02 EP claimed
EP-1432428-A1 Agent for colouring fibres containing keratin Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-4611747-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS Genep Inc. (US) 2025-09-10 EP disclosed
WO-2025122832-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS GENEP INC. (US) 2025-06-12 WO disclosed
CN-119912606-A Catalyst suitable for ethylene polymerization reaction and preparation method and application thereof 中国石油化工股份有限公司 2025-05-02 CN disclosed
WO-2024097171-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS GENEP INC. (US) 2024-05-10 WO disclosed
US-20230358767-A1 METHOD FOR REDUCING MEASUREMENT ERROR SEKISUI MEDICAL CO., LTD. (JP) 2023-11-09 US disclosed
US-11767336-B2 Organometallic cluster photoresists for EUV lithography TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2023-09-26 US disclosed
EP-4212627-A1 METHOD FOR REDUCING MEASUREMENT ERROR Sekisui Medical Co., Ltd. (JP) 2023-07-19 EP disclosed
CN-1751025-A Diamine derivatives DAIICHI SEIYAKU CO (JP) 2006-03-22 CN disclosed
US-20050090529-A1 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation PFIZER INC 2005-04-28 US disclosed
EP-1432428-A1 Agent for colouring fibres containing keratin Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP disclosed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO disclosed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP disclosed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP disclosed
WO-1995011002-A1 ETHANE DIONES FOR USE IN DYEING KERATIN-CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1995-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230358767-A1 METHOD FOR REDUCING MEASUREMENT ERROR CAT, MPO, UCHL1 CES2 103/4885CES1 267/4885ALOX15 592/4885
US-11767336-B2 Organometallic cluster photoresists for EUV lithography ETV6, CDV3, RUVBL2 CES2 2583/4885CES1 4767/4885ALOX15 3976/4885
US-20050090529-A1 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation CDK3, CDK4, CDK9 CES2 4836/4885CES1 4122/4885ALOX15 2114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.