Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | NR1D1 | P20393 | 8/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574578 | 0.80 | FBP1 (0.46) | TLR4TLR2HTTCYP1A2CYP2D6 | |
| SCHEMBL2574573 | 0.80 | FBP1 (0.46) | TLR4TLR2HTTCYP1A2CYP2D6 | |
| SCHEMBL27326670 | 0.76 | VCP (0.54) | VCPCHRNB2CHRNA4TLR4TLR2 | |
| SCHEMBL10511846 | 0.76 | KDM4E (0.46) | VCPCHRNB2CHRNA4NR1D1NR1H3 | |
| SCHEMBL27717225 | 0.71 | RIPK1 (0.49) | CHRNB2CHRNA4NR1D1NR1H3RIPK1 | |
| SCHEMBL27876990 | 0.70 | CHRNA7 (0.53) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| SCHEMBL3018840 | 0.70 | CHRNA7 (0.52) | CHRNB2CHRNA4NAPRTHTTCYP1A2 | |
| SCHEMBL9718704 | 0.69 | RIPK1 (0.47) | CHRNB2CHRNA4NR1D1NR1H3RIPK1 | |
| SCHEMBL9800154 | 0.69 | RIPK1 (0.47) | CHRNB2CHRNA4NR1D1NR1H3RIPK1 | |
| SCHEMBL9800159 | 0.69 | RIPK1 (0.47) | CHRNB2CHRNA4NR1D1NR1H3RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |