Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672444 | 0.88 | PLA2G7 (0.38) | ALDH1A1MEN1KMT2AMAPTSNCA | |
| SCHEMBL7666929 | 0.80 | ALDH1A1 (0.41) | PTGER1EGFRALDH1A1MEN1KMT2A | |
| SCHEMBL6979231 | 0.73 | EGFR (0.53) | PTGER1EGFRALDH1A1MEN1KMT2A | |
| SCHEMBL7668248 | 0.72 | IDH1 (0.32) | ALDH1A1MAPTHPGDBCHEACHE | |
| SCHEMBL7666688 | 0.70 | P2RX7 (0.35) | ALDH1A1MEN1KMT2AMAPTTOP2A | |
| SCHEMBL7670463 | 0.67 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL7666716 | 0.66 | SMN1; SMN2 (0.39) | ALDH1A1MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL7666630 | 0.64 | EGFR (0.47) | PTGER1EGFRALDH1A1MEN1KMT2A | |
| SCHEMBL7670591 | 0.64 | PDE3B (0.39) | ALDH1A1MAPTHPGDNR1H2TOP2A | |
| SCHEMBL7356620 | 0.63 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |