Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.30 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670903 | 0.90 | FPR1 (0.32) | — | |
| SCHEMBL7666967 | 0.89 | — | — | |
| SCHEMBL7666688 | 0.86 | P2RX7 (0.35) | ALDH1A1 | |
| SCHEMBL7673385 | 0.86 | LTA4H (0.42) | — | |
| SCHEMBL7672380 | 0.83 | NR1I2 (0.31) | — | |
| SCHEMBL7674409 | 0.83 | PLA2G7 (0.32) | — | |
| SCHEMBL7668248 | 0.83 | IDH1 (0.32) | ALDH1A1PLA2G4A | |
| SCHEMBL7674978 | 0.83 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL7669032 | 0.81 | LRRK2 (0.35) | ALDH1A1 | |
| SCHEMBL7674317 | 0.81 | PTK2 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |