Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CDK2 | P24941 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373589 | 0.75 | ALOX15 (1.00) | RAB9ANPC1SMN1; SMN2CDK2ALOX15 | |
| SCHEMBL25060915 | 0.75 | — | — | |
| SCHEMBL150787 | 0.74 | BCAT2 (0.53) | RAB9ANPC1CDK2PTPN1KMT2A | |
| SCHEMBL13446570 | 0.73 | — | — | |
| SCHEMBL1948472 | 0.72 | — | — | |
| N-Phenylbenzamide SCHEMBL31966 | 0.72 | SIRT1 (0.83) | RAB9ANPC1SMN1; SMN2HTTPTPN1 | |
| SCHEMBL1315526 | 0.72 | PTPN1 (0.87) | RAB9ANPC1HTTPTPN1KMT2A | |
| SCHEMBL24202631 | 0.72 | SIRT1 (0.83) | RAB9ANPC1SMN1; SMN2HTTPTPN1 | |
| N-Phenylbenzamide SCHEMBL5402750 | 0.72 | SIRT1 (0.83) | RAB9ANPC1SMN1; SMN2HTTPTPN1 | |
| SCHEMBL5020210 | 0.71 | KCNK3 (0.58) | RAB9ANPC1SMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | disclosed |