Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | WDR5 | P61964 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169302 | 0.80 | LMNA (0.44) | LMNASMN1; SMN2PKML3MBTL1ALDH1A1 | |
| SCHEMBL7169064 | 0.77 | TDP1 (0.40) | LMNASMN1; SMN2ALDH1A1HTTKMT2A | |
| SCHEMBL7172562 | 0.76 | LMNA (0.37) | LMNASMN1; SMN2PKML3MBTL1ALDH1A1 | |
| SCHEMBL7170239 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1ALDH1A1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL7669155 | 0.76 | LMNA (0.37) | LMNASMN1; SMN2PKML3MBTL1ALDH1A1 | |
| SCHEMBL27530283 | 0.73 | LMNA (0.49) | LMNASMN1; SMN2PKML3MBTL1HTR6 | |
| SCHEMBL27433750 | 0.68 | ALPL (0.48) | SMN1; SMN2ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL4884796 | 0.67 | MAPT (0.50) | LMNASMN1; SMN2ALDH1A1WDR5POLB | |
| SCHEMBL29509026 | 0.65 | ALDH1A1 (0.47) | LMNASMN1; SMN2PKML3MBTL1ALDH1A1 | |
| SCHEMBL5200902 | 0.65 | LMNA (0.46) | LMNASMN1; SMN2PKML3MBTL1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369057-B1 | VIRICIDES, IN PARTICULAR AGAINST RETROVIRUSES, HUMAN IMMUNODEFICIENCY VIRUS (HIV) | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |
| EP-0657166-A1 | Combination containing a quinoxaline and a nucleoside | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-14 | — | — | EP | disclosed |