Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668586 | 0.86 | HSD17B10 (0.43) | HTR2AHTR2CHSD17B10IDO1ADRA1A | |
| SCHEMBL3484107 | 0.85 | APLNR (0.46) | APLNRPOLBHTR2AHTR2CHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL10346000 | 0.83 | APLNR (0.44) | APLNRPOLBHTR2AHTR2CHSD17B10 | |
| SCHEMBL30486651 | 0.81 | APLNR (0.46) | APLNRPOLBHTR2AHTR2CCA12 | |
| SCHEMBL3527192 | 0.81 | APLNR (0.46) | APLNRPOLBHTR2AHTR2CCA12 | |
| SCHEMBL23704945 | 0.80 | HTR2A (0.43) | APLNRPOLBHTR2AHTR2CCA12 | |
| SCHEMBL9171486 | 0.79 | APLNR (0.44) | APLNRPOLBHTR2AHTR2CHSD17B10 | |
| SCHEMBL6603605 | 0.79 | APLNR (0.44) | APLNRPOLBHTR2AHTR2CCA12 | |
| SCHEMBL8640683 | 0.79 | IDO1 (0.48) | APLNRPOLBHTR2AHTR2CCA12 | |
| SCHEMBL6804542 | 0.79 | ALDH1A1 (0.49) | APLNRPOLBHTR2AHTR2CCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| CN-1284075-A | Novel compounds having CGMP-PDE inhibitory effect | MOCHIDA PHARM CO LTD (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |