Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001551 | 0.86 | HSD17B10 (0.44) | HSD17B10HTR1ASLC6A4IDO1ADRA1A | |
| SCHEMBL7674877 | 0.86 | APLNR (0.44) | HSD17B10IDO1ADRA1ATAAR1HPGD | |
| SCHEMBL15289008 | 0.84 | HTR1A (0.43) | HSD17B10HTR1ASLC6A4IDO1ADRA1A | |
| SCHEMBL7551792 | 0.83 | ADRA1A (0.48) | HTR1ASLC6A4IDO1ADRA1ATAAR1 | |
| SCHEMBL1058869 | 0.82 | HTR2A (0.44) | HSD17B10HTR1ASLC6A4IDO1ADRA1A | |
| SCHEMBL12428735 | 0.81 | HTR1A (0.44) | HTR1ASLC6A4IDO1ADRA1ATAAR1 | |
| SCHEMBL15882751 | 0.80 | HTR1A (0.43) | HSD17B10HTR1ASLC6A4IDO1ADRA1A | |
| SCHEMBL6401311 | 0.80 | ALDH1A1 (0.47) | HSD17B10HTR1ASLC6A4IDO1ADRA1A | |
| SCHEMBL791872 | 0.80 | IDO1 (0.46) | HSD17B10HTR1ASLC6A4IDO1ADRA1A | |
| SCHEMBL594784 | 0.80 | KDM4E (0.46) | HSD17B10HTR1ASLC6A4IDO1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023160672-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH LPA RECEPTOR ACTIVITY | LHOTSE BIO , INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| CN-101437826-A | Pentacyclic indole derivatives as antiviral agents | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-05-20 | — | — | CN | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| CN-1284075-A | Novel compounds having CGMP-PDE inhibitory effect | MOCHIDA PHARM CO LTD (JP) | 2001-02-14 | — | — | CN | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |