Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 6/20 | 0.47 |
| ▸ | METAP1 | P53582 | 6/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563351 | 0.83 | MMP9 (0.56) | ECE1GAA | |
| SCHEMBL7672369 | 0.81 | ECE1 (0.59) | ECE1GAA | |
| SCHEMBL27232779 | 0.81 | MEN1 (0.57) | LMNAGAAPDE2A | |
| SCHEMBL27222128 | 0.81 | MEN1 (0.57) | LMNAGAAPDE2A | |
| SCHEMBL7671952 | 0.79 | MMP9 (0.47) | ECE1GAA | |
| SCHEMBL4001238 | 0.78 | GPR84 (0.54) | GAA | |
| SCHEMBL7677146 | 0.78 | MAPT (0.44) | ECE1GAA | |
| SCHEMBL7868509 | 0.78 | LMNA (0.59) | SSTR4LMNAGAAMETAP2METAP1 | |
| SCHEMBL13797509 | 0.78 | LMNA (0.59) | SSTR4LMNAGAAMETAP2METAP1 | |
| SCHEMBL14521509 | 0.78 | LMNA (0.59) | SSTR4LMNAGAAMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |