Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732038 | 0.85 | ATM (0.51) | MAPTRAB9AATML3MBTL1CYP3A4 | |
| SCHEMBL3740424 | 0.84 | NR4A1 (0.51) | MAPTL3MBTL1CTSKCTSBCTSL | |
| SCHEMBL7860528 | 0.84 | MAPT (0.47) | MAPTRAB9AL3MBTL1CYP3A4CTSK | |
| SCHEMBL3727297 | 0.74 | CA2 (0.53) | ATMCTSKCTSBCTSLCTSS | |
| SCHEMBL3735287 | 0.74 | CA2 (0.49) | RAB9ACYP3A4CTSKCTSBCTSL | |
| SCHEMBL5898423 | 0.74 | CTSK (0.57) | CTSKCTSBCTSLCTSS | |
| SCHEMBL30016306 | 0.73 | CTSL (0.55) | RAB9AL3MBTL1CYP3A4ALDH1A1TSHR | |
| SCHEMBL3736355 | 0.73 | CTSB (0.57) | RAB9AATMCYP3A4CTSKCTSB | |
| SCHEMBL3740465 | 0.73 | ATM (0.55) | ATMCYP3A4ALDH1A1TSHRCTSK | |
| SCHEMBL28892051 | 0.73 | TRPM8 (0.62) | ATMALDH1A1CTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458772-B1 | Prodrugs | MEDIVIR AB (SE) | 2002-10-01 | — | — | US | disclosed |