Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674484 | 0.91 | KMT2A (0.47) | KIF11KMT2AMEN1ALDH1A1ABCG2 | |
| SCHEMBL7851436 | 0.88 | ABCG2 (0.42) | KIF11ABCG2DHODH | |
| SCHEMBL7683405 | 0.84 | KIF11 (0.38) | KIF11KMT2AMEN1ALDH1A1ABCG2 | |
| SCHEMBL7680379 | 0.81 | MAPT (0.51) | KIF11KMT2AMEN1ALDH1A1ABCG2 | |
| SCHEMBL7677069 | 0.79 | MEN1 (0.49) | KIF11KMT2AMEN1ALDH1A1ABCG2 | |
| SCHEMBL7853658 | 0.78 | SIRT1 (0.46) | KIF11ALDH1A1ABCG2MAPTLMNA | |
| SCHEMBL7681633 | 0.78 | MEN1 (0.48) | KIF11KMT2AMEN1ALDH1A1ABCG2 | |
| SCHEMBL7677783 | 0.78 | ABCG2 (0.52) | KIF11KMT2AMEN1ALDH1A1ABCG2 | |
| SCHEMBL7680170 | 0.77 | LMNA (0.52) | KIF11KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7680650 | 0.76 | MAPT (0.46) | KIF11KMT2AALDH1A1ABCG2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |