Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645703 | 0.91 | CTSK (0.46) | CTSKCA2CA1MAPK1PRKCA | |
| SCHEMBL2339946 | 0.86 | CTSK (0.51) | CTSKCA2CA1MAPK1PRKCA | |
| SCHEMBL6278113 | 0.86 | CA2 (0.45) | CTSKCA2CA1MAPK1MAPT | |
| SCHEMBL10694776 | 0.85 | PRKCA (0.44) | CTSKCA2CA1MAPK1PRKCA | |
| SCHEMBL7648142 | 0.84 | CA2 (0.48) | CA2MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL7645781 | 0.84 | CA2 (0.48) | CA2MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL7645775 | 0.84 | GPR84 (0.45) | CA2CA1MAPK1MAPTFDPS | |
| SCHEMBL6893821 | 0.83 | PRKCA (0.41) | CTSKCA2CA1MAPK1PRKCA | |
| SCHEMBL6893118 | 0.83 | ALDH1A1 (0.48) | CTSKCA2CA1MAPK1PRKCA | |
| SCHEMBL8518835 | 0.82 | GPR84 (0.48) | CA2MAPK1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764628-B1 | Diesters of pyrocarbonic acid, their preparation and their use | CIBA SC HOLDING AG (CH) | 2001-03-14 | — | — | EP | claimed |
| US-5750758-A | DEHYDRATION OF CARBONIC ACID | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-12 | — | — | US | claimed |
| US-6359122-B1 | Pyrocarbonic acid diesters and the preparation and use thereof | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-19 | — | — | US | disclosed |
| US-6222047-B1 | PIGMENT PRECURSORS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-04-24 | — | — | US | disclosed |
| US-5750758-A | DEHYDRATION OF CARBONIC ACID | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |