Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016823 | 0.78 | KDM4E (0.49) | METMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL830432 | 0.74 | ALDH3A1 (0.57) | MEN1KMT2AALDH3A1HTTGAA | |
| SCHEMBL19791848 | 0.71 | MET (0.64) | METRAPGEF4 | |
| SCHEMBL21295269 | 0.71 | LTA4H (0.38) | MEN1MAPTKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL7165820 | 0.70 | HTT (0.43) | METMAPK1MEN1MAPTKMT2A | |
| SCHEMBL31229913 | 0.69 | LTA4H (0.39) | MEN1MAPTKMT2ASMN1; SMN2LTA4H | |
| SCHEMBL5571659 | 0.68 | PARP1 (0.47) | METMEN1KMT2ALTA4H | |
| SCHEMBL1165560 | 0.67 | LTA4H (0.38) | KMT2ALTA4HPOLB | |
| SCHEMBL13296647 | 0.67 | LTA4H (0.38) | KMT2ALTA4HPOLB | |
| SCHEMBL256361 | 0.67 | LTA4H (0.41) | MEN1MAPTKMT2ALTA4HHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250337-A1 | SUBSTITUTED HOMOPIPERIDINYL BENZIMIDAZOLE ANALOGUES AS FUNDIC RELAXANTS | Janssen Pharmaceutica N.V. (BE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001046189-A1 | SUBSTITUTED HOMOPIPERIDINYL BENZIMIDAZOLE ANALOGUES AS FUNDIC RELAXANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-06-28 | — | — | WO | disclosed |