Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934753 | 0.85 | CYP4F2 (0.39) | TSHRALDH1A1PPARAGPR84TDP1 | |
| SCHEMBL6598371 | 0.84 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2797147 | 0.80 | TSHR (0.38) | TSHRALDH1A1AKR1B1CA2MAPK1 | |
| SCHEMBL1114580 | 0.77 | ACLY (0.38) | TSHRALDH1A1AKR1B1CA2MAPK1 | |
| SCHEMBL1902095 | 0.77 | AKR1B1 (0.40) | TSHRALDH1A1AKR1B1CA2MAPK1 | |
| SCHEMBL605019 | 0.77 | TSHR (0.43) | TSHRALDH1A1AKR1B1CA2MAPK1 | |
| SCHEMBL381209 | 0.77 | TSHR (0.43) | TSHRALDH1A1AKR1B1CA2MAPK1 | |
| SCHEMBL2103333 | 0.77 | TSHR (0.43) | TSHRALDH1A1AKR1B1CA2MAPK1 | |
| SCHEMBL1037903 | 0.76 | AKR1B1 (0.36) | TSHRALDH1A1AKR1B1PPARGPPARD | |
| SCHEMBL29275052 | 0.76 | ACLY (0.36) | TSHRALDH1A1AKR1B1CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350878-B1 | BASIFICATION AND IODINATION OF ALDEHYDE | NOVARTIS AG (CH) | 2002-02-26 | — | — | US | claimed |