Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684669 | 0.93 | MAPT (0.34) | SMN1; SMN2KMT2AMAPTF2ALDH1A1 | |
| SCHEMBL7685879 | 0.89 | MAPT (0.34) | KMT2AMAPTF2LMNAALDH1A1 | |
| SCHEMBL7675233 | 0.87 | ALDH1A1 (0.34) | SMN1; SMN2KMT2AMAPTF2LMNA | |
| SCHEMBL7678756 | 0.85 | HTT (0.38) | SMN1; SMN2MAPTLMNAALDH1A1HSD17B10 | |
| SCHEMBL7684146 | 0.84 | MAPT (0.35) | SMN1; SMN2KMT2AMAPTF2ALDH1A1 | |
| SCHEMBL7679296 | 0.84 | CNR1 (0.38) | KMT2AMEN1CNR2 | |
| SCHEMBL7679315 | 0.84 | ALDH1A1 (0.35) | SMN1; SMN2KMT2AMAPTF2LMNA | |
| SCHEMBL7685899 | 0.82 | ALDH1A1 (0.37) | SMN1; SMN2KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL7685639 | 0.79 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AMAPTF2LMNA | |
| SCHEMBL7679294 | 0.78 | ALDH1A1 (0.34) | SMN1; SMN2KMT2AMAPTF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |