Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684146 | 0.91 | MAPT (0.35) | MAPTKMT2AF2PDE4APDE4B | |
| SCHEMBL7679448 | 0.89 | SMN1; SMN2 (0.33) | MAPTKMT2AF2PDE4APDE4B | |
| SCHEMBL7685639 | 0.88 | ALDH1A1 (0.36) | MAPTKMT2AF2PDE4APDE4B | |
| SCHEMBL7684085 | 0.87 | PDE4D (0.40) | MAPTKMT2AF2PDE4APDE4B | |
| SCHEMBL7679294 | 0.85 | ALDH1A1 (0.34) | MAPTKMT2AF2PDE4APDE4B | |
| SCHEMBL7678830 | 0.83 | PDE4A (0.33) | MAPTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL7682616 | 0.83 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10L3MBTL1LMNA | |
| SCHEMBL7675254 | 0.82 | POLB (0.39) | KMT2APTGER4POLB | |
| SCHEMBL7686030 | 0.82 | PTGS2 (0.35) | MAPTKMT2AF2PDE4APDE4B | |
| SCHEMBL7684669 | 0.82 | MAPT (0.34) | MAPTKMT2AF2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |