Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686476 | 0.91 | GAA (0.35) | GAACA9CA12ELANETP53 | |
| SCHEMBL7686603 | 0.82 | GAA (0.35) | GAACA9CA12ELANETP53 | |
| SCHEMBL7954706 | 0.73 | ELANE (0.35) | GAACA9CA12ELANETP53 | |
| SCHEMBL7686165 | 0.72 | HTR7 (0.54) | — | |
| SCHEMBL7677803 | 0.68 | HTR7 (0.51) | — | |
| SCHEMBL23518159 | 0.67 | CA9 (0.41) | GAACA9CA12ELANETP53 | |
| SCHEMBL6996410 | 0.65 | LMNA (0.34) | — | |
| SCHEMBL24133108 | 0.63 | CA9 (0.39) | GAACA9CA12ELANETP53 | |
| SCHEMBL7683391 | 0.62 | TP53 (0.33) | GAACA9CA12ELANETP53 | |
| SCHEMBL6999769 | 0.61 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |