Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CCR9 | P51686 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679936 | 0.85 | EGLN1 (0.45) | KDM4EALDH1A1ATMKMT2ACYP1A2 | |
| SCHEMBL3958982 | 0.80 | CCR2 (0.56) | KDM4EALDH1A1KMT2ACYP1A2MEN1 | |
| SCHEMBL3757847 | 0.79 | GPR35 (0.48) | KDM4EALDH1A1ATMKMT2ACYP1A2 | |
| SCHEMBL15334966 | 0.77 | CNR2 (0.48) | KDM4EALDH1A1KMT2AMEN1CNR2 | |
| SCHEMBL2049484 | 0.76 | CNR2 (0.46) | KDM4EALDH1A1ATMKMT2ACYP1A2 | |
| SCHEMBL7684946 | 0.76 | NTRK1 (0.52) | KDM4EALDH1A1CYP1A2CCR9NTRK1 | |
| SCHEMBL15157126 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1KMT2ANTRK1 | |
| SCHEMBL3592491 | 0.74 | MTNR1A (0.52) | KDM4EALDH1A1KMT2A | |
| SCHEMBL3005616 | 0.74 | CCR2 (0.62) | KDM4EALDH1A1ATMKMT2ACYP1A2 | |
| SCHEMBL31091283 | 0.73 | CYP3A4 (0.42) | KDM4EATMKMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |