Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.39 |
| ▸ | MMP3 | P08254 | 6/20 | 0.39 |
| ▸ | MMP1 | P03956 | 5/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680126 | 1.00 | MMP13 (0.39) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7057190 | 0.92 | MMP3 (0.41) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7352231 | 0.90 | MMP3 (0.40) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7059119 | 0.90 | MMP13 (0.35) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7353097 | 0.86 | MMP1 (0.43) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7055845 | 0.86 | MMP1 (0.43) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7057754 | 0.86 | MMP3 (0.43) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7058579 | 0.85 | MMP3 (0.53) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7051935 | 0.84 | MMP1 (0.41) | MMP13MMP3MMP1MMP9MMP7 | |
| SCHEMBL7054506 | 0.83 | GAA (0.43) | MMP13MMP3MMP1MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489324-B2 | TREATING STROKE, ARHTRITIS, CANCER, TISSUE ULCERATION, DECUBITIS ULCER, RESTENOSIS, PERIODONTAL DISEASE, EPIDERMOLYSIS BULLOSA, SCLERITIS, PSORIASIS, AIDS, SEPSIS, AND SEPTIC SHOCK. | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-03 | — | — | US | disclosed |