Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 9/20 | 0.43 |
| ▸ | MMP13 | P45452 | 9/20 | 0.43 |
| ▸ | MMP9 | P14780 | 8/20 | 0.43 |
| ▸ | MMP3 | P08254 | 7/20 | 0.43 |
| ▸ | MMP7 | P09237 | 7/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353097 | 1.00 | MMP1 (0.43) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7057133 | 0.90 | MEN1 (0.36) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7057190 | 0.89 | MMP3 (0.41) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7352231 | 0.88 | MMP3 (0.40) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7680133 | 0.86 | MMP13 (0.39) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7680126 | 0.86 | MMP13 (0.39) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7058579 | 0.85 | MMP3 (0.53) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7052103 | 0.84 | MMP1 (0.41) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7056970 | 0.83 | MMP9 (0.44) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL7057754 | 0.81 | MMP3 (0.43) | MMP1MMP13MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030060473-A1 | Piperazine compounds as inhibitors of MMP or TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060473-A1 | Piperazine compounds as inhibitors of MMP or TNF | MMP2, MMP1, TNF | MMP1 2/4885MMP13 14/4885MMP9 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.