Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129574 | 0.89 | HPGDS (0.34) | ALDH1A1LMNA | |
| SCHEMBL7684740 | 0.77 | POLB (0.37) | ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL9811868 | 0.73 | HSD17B10 (0.32) | ALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10067534 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL7684320 | 0.73 | ALOX15 (0.49) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL8647610 | 0.72 | CYP1A2 (0.41) | ALDH1A1MAPTHPGDHTT | |
| SCHEMBL3706189 | 0.72 | KDM4E (0.42) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL311179 | 0.71 | KDM4E (0.35) | LMNAHCAR2 | |
| SCHEMBL1079256 | 0.71 | KDM4E (0.46) | ALDH1A1LMNAMAPTHPGDHTT | |
| SCHEMBL5172213 | 0.70 | ABCG2 (0.35) | ALDH1A1LMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359061-B1 | COMBINATORIAL LIBRARIES ARE USEFUL FOR SCREENING IN BIOLOGCAL ASSAYS IN ORDER TO IDENTIFY PHARMACEUTICALLY USEFUL COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2002-03-19 | — | — | US | disclosed |