Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679500 | 0.89 | CDK2 (0.43) | CDK2CDK4 | |
| SCHEMBL7682045 | 0.87 | CDK2 (0.43) | CDK2ALDH1A1MAPTKDM4ECDK4 | |
| SCHEMBL7677596 | 0.86 | CDK2 (0.41) | MARK4KMT2ACDK2LMNASMN1; SMN2 | |
| SCHEMBL7680034 | 0.86 | CDK2 (0.40) | MARK4CDK2MAPTCDK4 | |
| SCHEMBL7674349 | 0.86 | TRPV1 (0.40) | CDK2SRD5A2CDK4 | |
| SCHEMBL7675092 | 0.85 | AKT1 (0.47) | CDK2LMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7680199 | 0.84 | TLR7 (0.39) | CDK2MAPTCDK4 | |
| SCHEMBL7673955 | 0.84 | NPC1 (0.42) | MAOAMEN1KMT2ACDK2SMN1; SMN2 | |
| SCHEMBL7680009 | 0.83 | CDK2 (0.39) | CDK2NPC1RAB9ACDK4 | |
| SCHEMBL7676827 | 0.83 | ABCC9 (0.38) | CDK2ALDH1A1NPC1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |