Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113008 | 0.88 | HTT (0.49) | HTTKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL174242 | 0.80 | KDM4E (0.50) | HTTKMT2ALMNAL3MBTL1RAB9A | |
| SCHEMBL18929814 | 0.77 | TAAR1 (0.47) | HTTKMT2ALMNAALDH1A1CA1 | |
| SCHEMBL11836946 | 0.72 | LMNA (0.48) | HTTKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL4979740 | 0.72 | NOX1 (0.64) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4980435 | 0.71 | NR1H4 (0.46) | HTTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7421824 | 0.71 | LMNA (0.47) | HTTKMT2AMEN1LMNAL3MBTL1 | |
| SCHEMBL8612474 | 0.70 | ALDH1A1 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2001630 | 0.70 | TAS2R38 (0.46) | KMT2AMEN1ALDH1A1NPC1PKM | |
| Bromide SCHEMBL5466183 | 0.70 | NR1H4 (0.44) | HTTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376538-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASES | BIOGEN, INC. | 2002-04-23 | — | — | US | claimed |