Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683472 | 0.86 | MAP1LC3B (0.47) | ALDH1A1MAPK1TP53HPGDHSD17B10 | |
| SCHEMBL7689340 | 0.83 | LMNA (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL7685368 | 0.83 | LMNA (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL7680888 | 0.76 | MAP1LC3B (0.51) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL7689110 | 0.74 | KDM1A (0.33) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL7689107 | 0.74 | KDM1A (0.33) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL7687762 | 0.72 | POLB (0.50) | ALDH1A1KMT2AMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL7689326 | 0.71 | GRM7 (0.42) | ALDH1A1KMT2ASMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL7678724 | 0.71 | LMNA (0.34) | ALDH1A1SMN1; SMN2MAPK1HPGDHSD17B10 | |
| SCHEMBL7689174 | 0.71 | LDHA (0.40) | ALDH1A1SMN1; SMN2LMNAMAP1LC3BLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |